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Mark S Anderson Selected Research

Autoantigens

3/2022Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq.
11/2021Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium.
1/2020High-resolution epitope mapping of anti-Hu and anti-Yo autoimmunity by programmable phage display.
1/2020Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq.
1/2020GILT in Thymic Epithelial Cells Facilitates Central CD4 T Cell Tolerance to a Tissue-Restricted, Melanoma-Associated Self-Antigen.
1/2017Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.
12/2016Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4.
6/2015Transglutaminase 4 as a prostate autoantigen in male subfertility.
4/2015Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens.
5/2014Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance.
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Mark S Anderson Research Topics

Disease

15Autoimmune Diseases (Autoimmune Disease)
03/2022 - 11/2002
11Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2022 - 01/2005
8COVID-19
03/2022 - 10/2020
7Neoplasms (Cancer)
01/2022 - 04/2014
5Autoimmune Polyendocrinopathies (Schmidt Syndrome)
01/2017 - 11/2006
4type 1 Autoimmune polyendocrinopathy syndrome
10/2016 - 12/2013
3Pneumonia (Pneumonitis)
03/2022 - 01/2021
3Infections
01/2017 - 12/2013
3Interstitial Lung Diseases (Interstitial Lung Disease)
06/2015 - 12/2009
3Inflammation (Inflammations)
06/2014 - 01/2008
2Melanoma (Melanoma, Malignant)
01/2020 - 01/2017
2Genetic Predisposition to Disease (Genetic Predisposition)
01/2020 - 01/2017
2Autoimmune Hepatitis
01/2017 - 04/2015
2Peripheral Nervous System Diseases (PNS Diseases)
05/2012 - 03/2009
2Dry Eye Syndromes (Dry Eye Syndrome)
04/2010 - 01/2008
1Mucocutaneous Lymph Node Syndrome (Kawasaki Disease)
03/2022
1COVID-19 related pediatric multisystem inflammatory disease
03/2022
1Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy)
01/2022
1Lipodystrophy
01/2022
1Panniculitis
01/2022
1Candidiasis (Moniliasis)
09/2021
1Mycoses (Diseases, Fungus)
01/2021
1Chronic Pancreatitis
01/2021
1Asymptomatic Infections
01/2021
1Nervous System Diseases (Neurological Disorders)
01/2020
1Encephalitis (Encephalitis, Rasmussen)
01/2020
1Margins of Excision
01/2020
1Adenocarcinoma
01/2019
1Colitis
01/2019
1Hereditary pancreatitis
01/2019
1X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation
01/2019
1Pancreatitis
01/2019
1Rheumatoid Arthritis
01/2018
1Diabetes Mellitus
01/2018
1Primary Ovarian Insufficiency
01/2017
1Wrist Fractures
01/2017
1Neuromyelitis Optica (Devic's Disease)
12/2016
1Chronic Kidney Failure (Chronic Renal Failure)
10/2016
1Interstitial Nephritis (Tubulointerstitial Nephritis)
10/2016
1Male Infertility (Male Sterility)
06/2015
1Joint Diseases (Joint Disease)
06/2015
1Arthritis (Polyarthritis)
06/2015
1Uveitis
06/2014
1Fibrous Dysplasia of Bone
04/2014
1Bone Diseases (Bone Disease)
04/2014
1hereditary expansile Polyostotic osteolytic dysplasia
04/2014

Drug/Important Bio-Agent (IBA)

18AutoantigensIBA
03/2022 - 11/2006
17AutoantibodiesIBA
01/2022 - 01/2005
10AntigensIBA
03/2022 - 11/2006
7Proteins (Proteins, Gene)FDA Link
03/2022 - 01/2008
5Insulin (Novolin)FDA Link
01/2022 - 11/2017
5EpitopesIBA
09/2021 - 01/2018
5InterferonsIBA
03/2021 - 11/2007
4Interferon Type IIBA
09/2021 - 11/2007
3AntibodiesIBA
10/2020 - 11/2007
2Transcription Factors (Transcription Factor)IBA
01/2020 - 11/2002
2Peptides (Polypeptides)IBA
01/2020 - 01/2018
2T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2019 - 03/2009
2Biomarkers (Surrogate Marker)IBA
04/2014 - 01/2008
12- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA
03/2022
1Perilipin-1IBA
01/2022
1RNA (Ribonucleic Acid)IBA
03/2021
1GemininIBA
01/2021
1cyclopropapyrroloindoleIBA
01/2021
1Prednisolone (Predate)FDA LinkGeneric
01/2021
1STAT1 Transcription FactorIBA
01/2021
1Janus KinasesIBA
01/2021
1Immunoglobulin G (IgG)IBA
10/2020
1EnzymesIBA
10/2020
1Immunoglobulin M (IgM)IBA
10/2020
1ImmunosorbentsIBA
10/2020
1Oxidoreductases (Dehydrogenase)IBA
01/2020
1Sulfhydryl Compounds (Thiols)IBA
01/2020
1DisulfidesIBA
01/2020
1Biological ProductsIBA
01/2020
1Monophenol Monooxygenase (Tyrosinase)IBA
01/2020
1Pancreatic Elastase (Elastase)IBA
01/2019
1Interleukin-2 (IL2)IBA
01/2019
1Mutant Proteins (Protein, Mutant)IBA
01/2019
1TrypsinIBA
01/2019
1Peptide Hydrolases (Proteases)FDA Link
01/2019
1SandIBA
01/2018
1AIRE ProteinIBA
01/2017
1formiminotetrahydrofolate cyclodeaminaseIBA
01/2017
1Nuclear Antigens (Extractable Nuclear Antigens)IBA
01/2017
1Immune Checkpoint ProteinsIBA
01/2017
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
12/2016
1Aquaporins (Water Channels)IBA
10/2016
1ProteomeIBA
02/2016
1transglutaminase 4IBA
06/2015
1Carrier Proteins (Binding Protein)IBA
06/2015
1Retinaldehyde (Retinal)IBA
06/2014
1Protein Sorting Signals (Signal Peptide)IBA
04/2014
1Codon (Codons)IBA
04/2014

Therapy/Procedure

4Therapeutics
01/2020 - 09/2008
2Immunotherapy
01/2022 - 01/2019
2Glycemic Control
01/2020 - 01/2020
1Artificial Respiration (Mechanical Ventilation)
01/2021
1Replacement Arthroplasty
01/2020
1Bone Wires
01/2017